Lewis and Clark Community College is a two-year higher education institution with multiple campuses, a river research center, a humanities center, a training center and Community Education Centers located throughout the more than 220,000-person college district, which reaches into seven counties.

In addition to offering associate degrees and certificates in more than 40 career programs and numerous transfer options, the college has something for just about everyone, including College for Kids, a nationally accredited dual credit program for high school students, GED completion and a robust Workforce Training Program, affiliated with the Houston Area Safety Council. Several colleges and universities also offer bachelor and master degree programs on Lewis and Clark's campus.

The college was founded in 1970 and began with 450 students. Today, it serves approximately 15,000 students annually and is a national and state award winning standout among Illinois community colleges. 

Lewis and Clark employs 636 employees and adds $338.5 million in regional income annually, which represents 4.6 percent of the regional economy.

The Godfrey campus is also unique – known for its beautiful, historic location on the grounds of the former Monticello College, the second oldest all-female college in the nation. The campus also features a number of eye-catching sculptures and fountains as part of the Monticello Sculpture Gardens, a Signature Garden site for the Missouri Botanical Gardens, and a botanic garden in its own right.

The buildings on the N.O. Nelson Campus in Edwardsville were on Illinois' list of "Ten Most Endangered Historic Sites" prior to Lewis and Clark purchasing the complex and renovating the buildings. The campus is now home to more than 1,500 students and numerous community events, making this restoration one of the most successful preservation initiatives in Illinois.

Lewis and Clark is dedicated to public engagement, from "greening" the campus, reducing the college's carbon footprint and providing technical assistance in sustainable practices and education, to delivering affordable healthcare to underserved populations throughout the district with a Mobile Health Unit and a federally-funded Family Health Clinic – currently the only nurse practitioner clinic operated by a community college.