The University of Guelph main campus covers 330 hectares (817 acres) in the city of Guelph (an hour’s drive West of Toronto), with a mix of classic and modern architecture. It has one of the largest and best residence systems in Canada, with a variety of living options for students and 16 different dining venues. There is excellent public transportation around Guelph; the city also has many bike lanes and bike trails and cycling is supported on campus as well.

Students enjoy many support services, including a large Athletics Centre, a Health Centre, Co-operative Education and Career Services, and services for international students. The large, modern library has programs for those needing assistance with writing and study skills in all courses and provides space for people to study alone or with groups.

In partnership with Humber College, the University of Guelph-Humber offers additional courses through the Humber College campus in Toronto. The Ontario Agriculture College has a satellite campus, Ridgetown in southwestern Ontario offering diploma, certificate and apprenticeship programs.